Paving the way to better care
A public-private international research collaboration aiming to personalise prevention and treatment of cardiovascular disease.
The challenge of cardiovascular disease
Cardiovascular disease (CVD) is the most common cause of death worldwide and has an incredibly large impact on people’s lives and wellbeing. The combination of an ageing population, unhealthy lifestyle, and increased numbers of risk factors, like hypertension, dyslipidemia, diabetes, and chronic kidney disease has led to a rise in the number of patients with CVD, reaching over 85 million in Europe alone.
Despite scientific advancements, the combination of risk factors linked to CVD and the presence of co-morbidities have made treatment difficult, making it urgent to address the complexity of CVD.
iCARE4CVD's vision is to work towards a future where CVD is better understood, more effectively treated, and less devastating for individuals and communities.
Number of people affected by CVD
> 500 million worldwide
Number of people that die from CVD
~ 17 million worldwide
About iCARE4VD
iCARE4CVD is an international, public-private research project that brings together 33 academic and industry partners united in the pursuit of improving the health of patients with CVD. The project will run for 4.5 years, led by University of Maastricht and Novo Nordisk.
iCARE4CVD aims to improve four key areas of current CVD healthcare by:
- Enhancing early diagnosis of patients at risk of cardiovascular disease
- Developing and assigning risk levels to patients, defining those who need an urgent intervention
- Creating AI-based tools to predict how individual patients will respond to treatment
- Ensuring the inclusion of outcomes that patients want, by incorporating their perspectives into every area of our work
Number of partners
33 leading international partners from civil society, academia, and industry
Amount of funding
22 million euros
The years it will run for
4.5 years
The project will achieve this by:
Collecting large amounts of patient cohorts...
covering patients of all CVD stages - from early risk to established heart failure
Generating a federated database...
to ensure private and confidential remote access to data on an individual level
Determining the value of biomarkers from different sources...
such as blood, imaging, digital wearables, to support early detection, monitoring, and treatment guidance for the entire spectrum of patients
Conducting in-depth qualitative research with patients and other stakeholders...
to build a motivational framework for self-care by patients and ensure their needs are incorporated into the outputs of the project
Developing artificial intelligence (AI)-based models to support diagnosis and predict risk and treatment responses...
to map the complete patient journey and response to interventions in CVD
Validating AI-based models prospectively towards precision medicine...
enabling the development of personalized care pathways
iCARE4CVD partners
iCARE4CVD brings together 33 leading international partners from civil society, academia and industry, and is lead by Maastricht University and global
healthcare company Novo Nordisk.
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