More Data, Better Care? The Promise and Reality of Digital Biomarkers in Cardiovascular Disease
We have more data on our hearts than ever before. Smartwatches track our rhythm around the clock. Implanted sensors monitor pressure and flow. Algorithms flag irregularities before symptoms appear. So why are we still diagnosing cardiovascular disease too late?
Can AI make heart failure evidence reviews faster and more reliable? New iCARE4CVD research puts it to the test

Screening thousands of research papers is one of the most time-consuming steps in evidence synthesis. A new study from the iCARE4CVD consortium asks whether large language models can do it reliably — and at scale.
Prediction or speculation: heart failure models for diabetes – An Editorial comment from iCARE4CVD

Can we predict heart failure in people with diabetes, or are we merely speculating? That is the question explored in a recent iCARE4CVD editorial, which discusses a large meta-analysis evaluating more than 50 prediction models designed to identify individuals with type 2 diabetes who are at risk of developing heart failure or being hospitalised because of it.
The Precision Moonshot: Redefining Cardiovascular Care for 85 Million Europeans
Cardiovascular disease affects 85 million Europeans, yet most patients are still treated as averages rather than individuals. In this article, our leading experts explore how personalised medicine could change that—transforming diagnosis, risk prediction, and treatment. They also unpack the barriers holding progress back, from fragmented data to outdated reimbursement models, and what it will take to bring truly patient-centred care into everyday practice.
The right treatment for the right patient: Rethinking heart failure care
Heart failure is a leading cause of hospitalisation in Europe, especially among older adults, and remains complex to treat, particularly alongside other conditions. Despite advances, outcomes still vary, pointing to the need for more tailored care. In this article, Prof. Hans-Peter Brunner-La Rocca explores what lies ahead for heart failure care.
“Suddenly, you are a patient 24 hours a day” – A patient perspective on living with heart failure
Heart failure affects millions worldwide, yet no two experiences are the same, shaping daily life in deeply personal ways. As care becomes more personalised, patient voices are increasingly vital. In this article, Max Groenhart shares his journey with heart failure and explains why involving patients in research is key to improving outcomes.
Connecting Health Data for Better Heart Failure Monitoring (SWAT4HCLS conference)
At the SWAT4HCLS conference, iCARE4CVD presented new research introducing the Digital Biomarker Ontology (DBO), building on earlier work such as CMEO to tackle a key challenge in digital health: fragmented patient data across devices and systems.
CMEO: making heart disease and clinical studies easier to find, compare, and reuse
Across Europe, vast amounts of heart disease data already exist—but they are often difficult to find, compare, and reuse. Our latest research introduces CMEO, a novel approach that organises information about studies, helping researchers understand what was measured, how it was done, and under which conditions data can be reused—without accessing patient data.
Beyond medical results: Using Patient-Reported Outcomes and Experiences in heart care – a scoping review
In a recent scoping review, we examined 390 studies to understand how patient-reported outcomes and experiences are used in heart care—and why patient voices are still not fully heard.
iCARE4CVD salutes the new EU cardiovascular Health Plan!
With the new EU Cardiovascular Health Plan launched – iCARE4CVD welcomes the strong alignment between the Plan’s priorities and the recommendations put forward by the consortium.